Dr. Agnes Zybura, Scientist, Molecular Bioanalysis
Dr. Agnes Zybura has extensive knowledge in the fields of molecular neurobiology, pharmacology and biochemistry with expertise in signal transduction pathways, sodium channel biology, electrophysiology, fluorescent imaging techniques, cell culture and PCR-based assays. She serves as a QC scientist within the Molecular Bioanalysis group at Labcorp (Greenfield) where she is responsible for developing and validating qPCR-/dPCR-based assays in support of biodistribution and vector shedding studies in accordance with applicable regulatory guidelines (e.g., GLP, GCP/CLIA). Together with her team in Molecular Bioanalysis, Agnes supports a wide variety of projects in the cell and gene therapy space ranging from early development to regulated clinical trials.
Prior to joining Labcorp Biopharmaceutical CMC Services, Agnes earned her PhD in medical neuroscience at the Indiana University School of Medicine where she discovered a novel mechanism involving kinase regulation of a voltage-gated sodium channel in modulating neuronal excitability. Her work continued as a postdoctoral researcher at Indiana University-Purdue University Indianapolis investigating neuronal effects and potential therapeutic treatments of epilepsy-associated genetic mutations. Agnes' work is published in several peer-reviewed publications and has been presented at international meetings.